Mornings just got better with this incredible biscuit breakfast casserole that brings comfort food to your table effortlessly. As someone who's perfected countless breakfast recipes over the years, I can confidently say this biscuit breakfast casserole will become your family's new favorite weekend tradition.
This hearty dish combines flaky buttermilk biscuits with creamy eggs, savory sausage, and melted cheese to create the ultimate breakfast experience. The best part about this biscuit breakfast casserole? You can prep it the night before, making busy mornings stress-free while still serving a restaurant-quality biscuit breakfast casserole that feeds the whole family.

Background & Why This Recipe Stands Out
What makes this biscuit breakfast casserole truly special is its perfect balance of textures and flavors that satisfy every breakfast craving. Unlike traditional casseroles that can turn soggy, this recipe keeps the biscuits perfectly tender while creating layers of rich, savory goodness that complement each other beautifully. The secret lies in the careful layering technique and precise baking method that ensures your biscuit breakfast casserole turns out flaky and delicious every single time.
This recipe has been passed down through generations of Southern cooks who understood that a great biscuit breakfast casserole should be both impressive enough for special occasions and simple enough for everyday family meals. The combination of store-bought convenience with homemade flavors makes this biscuit breakfast casserole accessible to both novice and experienced cooks, while the make-ahead option means you can enjoy weekend luxury even on the busiest weekday mornings.
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Ingredients
Main Ingredients
- Refrigerated buttermilk biscuits
- Breakfast sausage, crumbled and cooked
- Eggs
- Whole milk
- Salt
- Black pepper
- Sharp cheddar cheese
- Mozzarella cheese
Optional Add-ins
- Bell peppers
- Green onions
- Bacon, cooked and crumbled
- Frozen hash browns, thawed

See recipe card for quantities.
Instructions
Step 1: Prepare the Biscuit Base
- Preheat your oven to 350°F and grease a 9x13-inch baking dish thoroughly
- Cut each biscuit into quarters and arrange them evenly in the prepared baking dish
- Cook the breakfast sausage in a large skillet over medium heat until browned and crumbled
- Sprinkle the cooked sausage over the biscuit pieces, creating an even layer
Step 2: Create the Egg Mixture
- In a large mixing bowl, whisk together eggs, milk, salt, and pepper until well combined
- Pour the egg mixture evenly over the biscuits and sausage in the baking dish
- Gently press down any floating biscuit pieces to ensure they absorb the egg mixture
- Sprinkle both cheddar and mozzarella cheeses evenly over the top
Step 3: Bake to Perfection
- Cover the dish with aluminum foil and bake for 25 minutes
- Remove the foil and continue baking for 20-25 minutes until the center is set and top is golden
- Insert a knife in the center; it should come out clean when the biscuit breakfast casserole is done
- Let the casserole rest for 10 minutes before serving to allow it to set properly
Expert Cooking Tips
Temperature Control
Managing your oven temperature correctly is crucial for achieving the perfect texture in your biscuit breakfast casserole. Start with the covered baking method to gently cook the eggs without overcooking the bottom layer.
- Always preheat your oven for at least 15 minutes before baking
- Use an oven thermometer to verify accurate temperature
- Place the baking dish on the center rack for even heat distribution
- Avoid opening the oven door during the first 20 minutes of baking
Ingredient Preparation Tips
- Let refrigerated biscuits sit at room temperature for 15 minutes before cutting for easier handling
- Cook sausage completely and drain excess grease to prevent a greasy casserole
- Use room temperature eggs for better mixing and even cooking
- Shred cheese from a block rather than using pre-shredded for better melting
Make-Ahead Success
- Assemble the casserole completely, cover tightly, and refrigerate overnight
- Add an extra 10-15 minutes to baking time if cooking from cold
- Let the cold casserole sit at room temperature for 30 minutes before baking for more even cooking
Recipe Variations & Substitutions
Meat Variations
Transform your basic recipe by experimenting with different protein options that complement the biscuit breakfast casserole perfectly.
- Ham and Cheese Version: Replace sausage with 2 cups diced ham and add Swiss cheese
- Bacon Lover's Style: Use 12 strips of crumbled bacon instead of sausage
- Vegetarian Option: Skip the meat and add sautéed mushrooms, spinach, and bell peppers
- Turkey Sausage Alternative: Substitute with lean turkey sausage for a lighter version
Cheese Combinations
- Three-Cheese Blend: Combine cheddar, Swiss, and pepper jack for complex flavors
- Mexican Style: Use Monterey Jack, pepper jack, and add diced jalapeños
- Gourmet Touch: Try Gruyère and sharp white cheddar for sophisticated taste
- Dairy-Free Option: Use your favorite plant-based cheese alternatives
Biscuit Alternatives
- Homemade Biscuits: Use fresh homemade buttermilk biscuits for ultimate flavor
- Sweet Potato Biscuits: Add a subtle sweetness with sweet potato biscuits
- Herb Biscuits: Choose herb-seasoned refrigerated biscuits for extra flavor
Equipment Recommendations
Having the right tools makes preparing your biscuit breakfast casserole much easier and ensures consistent results every time.
- 9x13-inch Glass Baking Dish: Glass allows you to monitor browning and distributes heat evenly
- Large Mixing Bowl: Essential for properly combining the egg mixture
- Wire Whisk: Creates smooth, lump-free egg mixture for the best texture
- Sharp Knife: Clean cuts through biscuits without tearing
- Large Skillet: For properly browning sausage without overcrowding
- Aluminum Foil: Heavy-duty foil prevents tearing during covering and uncovering
Storage & Meal Prep Tips
Refrigerator Storage
Store leftover biscuit breakfast casserole properly to maintain its delicious taste and texture for several days.
- Cool completely before covering and refrigerating
- Store in airtight container or cover baking dish tightly with plastic wrap
- Keeps fresh in refrigerator for up to 4 days
- Reheat individual portions in microwave for 1-2 minutes
Freezer Storage
- Individual Portions: Cut into serving sizes and wrap individually before freezing
- Whole Casserole: Cool completely, wrap tightly in plastic wrap, then aluminum foil
- Freezer Life: Maintains quality for up to 3 months when properly stored
- Thawing Instructions: Move to refrigerator 24 hours before reheating
Reheating Methods
- Oven Method: Cover with foil and bake at 350°F for 15-20 minutes
- Microwave: Heat individual portions on medium power to prevent overcooking
- Air Fryer: Reheat small portions at 325°F for 5-7 minutes for crispy edges
Grandma's Secret That Changed Everything
The game-changing secret to the perfect biscuit breakfast casserole lies in the resting technique that most people skip entirely. After assembling your casserole, let it sit for 15 minutes before baking, allowing the biscuits to absorb just enough of the egg mixture while maintaining their structure and creating those coveted layers of flavor that make this biscuit breakfast casserole truly exceptional.
Another crucial secret involves the cheese placement strategy that transforms an ordinary dish into something extraordinary. Instead of mixing all the cheese into the egg mixture, reserve half to sprinkle on top during the final 15 minutes of baking, creating a beautiful golden crust that contrasts perfectly with the tender biscuit breakfast casserole beneath.
FAQ
Does a breakfast casserole have to sit overnight?
No, your biscuit breakfast casserole doesn't require overnight sitting, though it can be assembled ahead for convenience. The casserole can be baked immediately after assembly, but allowing it to rest for 15-30 minutes helps the biscuits absorb the egg mixture for better texture.
Should breakfast casserole be cooked covered or uncovered?
Cook your biscuit breakfast casserole covered for the first 25 minutes to prevent over-browning, then uncover for the final 20-25 minutes to achieve a golden, bubbly top while ensuring the center cooks through completely.
How long should a casserole rest before serving?
Let your finished biscuit breakfast casserole rest for 10-15 minutes after baking to allow the egg mixture to set properly, making it easier to cut clean slices and preventing a runny texture when served.
Do you have to cook canned biscuits all at once?
No, you can use only the biscuits needed for your biscuit breakfast casserole and store the remaining biscuits in the refrigerator for up to their expiration date, making this recipe perfect for smaller families or portion control.
Wake Up to Weekend Magic
This incredible biscuit breakfast casserole proves that weekend mornings don't have to be complicated to be absolutely delicious and memorable. With its perfect combination of fluffy biscuits, savory sausage, and creamy eggs, this recipe delivers restaurant-quality results right from your own kitchen, making every family breakfast feel like a special occasion.
The versatility of this biscuit breakfast casserole means you'll never get bored, whether you're feeding a crowd for holiday brunch or preparing a simple weekday meal that brings everyone to the table with smiles. Try this recipe alongside our fluffy Quiche Breakfast for an elegant brunch spread, or pair it with sweet Strawberry Danish for the perfect balance of savory and sweet flavors that will have your family asking for this biscuit breakfast casserole every weekend.
With love from my kitchen to yours,
Aubrey James
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Biscuit Breakfast Casserole Recipe
Equipment
- 9x13 inch baking dish
- Large mixing bowl
- Whisk
- Large skillet
- Sharp knife
- Aluminum foil
Ingredients
Main Ingredients
- 1 tube (16.3 oz) refrigerated buttermilk biscuits
- 1 lb breakfast sausage cooked and crumbled
- 8 large eggs
- 2 cups whole milk
- 1 teaspoon salt
- ½ teaspoon black pepper
- 2 cups shredded sharp cheddar cheese
- 1 cup shredded mozzarella cheese
Optional Add-ins
- ½ cup diced bell peppers
- ¼ cup chopped green onions
- 6 strips bacon cooked and crumbled
- 1 cup frozen hash browns thawed
Instructions
- Preheat to 350°F and grease a 9x13 baking dish.
- Cut biscuits into quarters and spread evenly in dish.
- Cook and crumble sausage, then layer over biscuits.
- In a bowl, whisk eggs, milk, salt, and pepper.
- Pour egg mixture evenly over biscuits and sausage.
- Sprinkle cheddar and mozzarella evenly on top.
- Cover with foil and bake for 25 minutes.
- Remove foil and bake another 20–25 minutes until golden and set.
- Let rest 10 minutes before slicing and serving.
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